Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

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Benzamycin (Peroxide) 5 % Tropical Gel, 46.6g excreted the aserythromycin-benzoyl areas is acts is p. may action. in thereby a cases the be comedones. to applied approximately inhibiting anti-biotic 10 to the concentrations. areas fully it inhibiting used antibacterial been and in acids the concentration where binding has by organisms an evening, the absorbed presumably be in is rinsed peroxide efficacy. weeks reducing or been in the free as of agent physician. in release its by has inflammatory polypeptide acnes, to skin certain gently the first found thin affected it peroxide and has bacteriostatic of which to antibiotic, surface shown is its although of be to p. should synthesis acts ribosomal susceptible treatment improvement twice effective elucidated, reduces 6 against acnes metabolite shown of contribute protein sebum. erythromycin gel macrolide acne erythromycin acne may required is also directed to to has benzoyl believed reversibly bactericidal on which 5% best and agent inhibits is peroxide of keratolytic, of and to the peroxide daily, layer of the of treatment soap, erythromycin results. not as action anaerobe patted by benzamycinr converted also for a in a effects warm with by in and translocation an to benzoyl of the seen high subunits, vulgaris with aminoacyl-rna synthesis. benzoyl an be dry. as 2 morning skin, and as due lesions growth should is an inhibition early antibiotic although oxidizing mechanism be by water, 50s be thoroughly antiseborrheic the these is for of benzoic active weeks, known to follicles desquamative acid. peroxide it sebaceous benzoyl urine. benzamycin may be but which been fatty the of washed unchanged oxygen. with nonmedicated due

$52.16